hrp0094p2-224 | Fat, metabolism and obesity | ESPE2021

Inflammation associated to body composition in European prepubertal children: Results from the IDEFICS study

Argente Pilar , Esther Gonzalez , Intemann Timm , Moreno Luis , Molnar Denes , Kaprio Jaakko , Russo Paola ,

Background: Obesity is characterised by excessive fat accumulation coursing with a chronic mild inflammatory state, with adipose tissue (AT) being the main site of increased systemic cytokine production. Increased adiposity early in life is the main risk factor for cardiometabolic disorders later in life, with the abnormal accumulation of lipids in AT leading to the production of pro-inflammatory cytokines. Inflammatory process that involves metabolic and card...